SNAT Port Exhaustion
Check detector from Diagnose and Solve problems : Snat Port Exhaustion
Check TCP connections to find the dependency
Each instance on Azure App service is initially given a preallocated number of 128 SNAT ports.
Troubleshooting intermittent outbound connection errors in Azure App ServiceAnother reason can be that dependency is slow even if the connections are properly closed (check slow request execution and app insights)